Studies on the Dd antigen-antibody system. I. The nature of antigen Dd and its antibodies

Summary The nature of antigen Dd, an antigen present in the extracts of human dandruff which precipitates human sera selectively, and antibodies reacting with it are reported.This work was supported through U.G.C. Grant No. F.23-230/75/SR II. H.K. participated in this study, first as J.R.F. of U.G.C. and then as S.R.F. of I.C.M.R. We are grateful to Dr Baruch S. Blumberg for his invaluable suggestions and to Professor H. Walter for the gift of IgG, IgM and IgA immune sera.     

砜基碳负离子的选择性环合反应

比较1，1－双（2－叔丁基砜乙基）十二烷基苯基砜（1）双碳负离子在不同条件下的环合反应结果，控制反应条件，在铁催化下可以生成偶联糁烯化的环烯产物（2）为主要产物；不加催化剂，加热回流反应得到分子内亲核取代反应产物环丙烷化合物（3）。     

The Study of the Grit-blasting Parameters and Their Effects on the Adhesive Strength of the Plasma Sprayed Coatings

Surface Preparation is very important in adhesive b on ding of spray coatings to the surface of a work piece. The common practice is gr it-blasting of the surface before subjecting it to the spray coating process. In this study, grit-blasting of an AISI 4130 steel (of different heat treatmen ts) with Al 2O 3 particles was studied. Various grit-blasting parameters such as blasting particle size, the distance between blasting nozzle and the work pi ece (25, 30 and 40 cm.), blasting pressure (3,4,5,6 and ...     

采用交流能源的低功耗DCVSL电路研究

从改变CMOS电路中能量转换模式的观点出发，研究利用渐变功率时钟的低功耗CMOS电路设计. 首先讨论钟控功率信号的代数表示及有关性质，然后归纳采用直流能源的互补CMOS逻辑门转化为采用交流能源的钟控CMOS门电路的设计过程. 在此基础上进一步提出采用交流能源的DCVSL电路设计. 采用正弦功率时钟的PSPICE模拟证实了钟控DCVSL电路具有正确的逻辑功能及低功耗工作的特点. 最后提出了一种将钟控信号转换为标准CMOS逻辑电平的接口电路并用计算机模拟验证了它的有效性.     

Increased assembly of cytoskeletal proteins associated with the transformation of human liver cells into fibroblast-like cells.

A topoisomerase II inhibitor, novobiocin, and a deacetylase inhibitor, butyrate, synergistically transformed human liver cells into fibroblast-like cells. This morphological change was associated with an increased production of procollagen type III peptide and a simultaneous assembly of actin, tubulin, vimentin and cytokeratin. Novobiocin and butyrate had no marked effect on the phosphorylation state of cytokeratin proteins, but synergistically enhanced [3H]acetate uptake. From these results, it can be speculated that protein acetylation plays an important role in inducing the assembly of cytoskeletal proteins and the morphological transformation of human liver cells.     

A study of macromolecular diffusion through native porcine mucus.

A diffusion chamber technique based on time-lag analysis for the estimation of effective diffusion coefficients of radiolabelled macromolecules of varying molecular weights through native mucus gel is reported. For all solutes studied, a reduction in effective diffusion coefficients was observed with a retardation of solute flux in both aqueous and mucus layers. Over the molecular weight range of solutes investigated (126-186,000 Daltons), a consistent effect of molecular weight was evident with regard to the retarding effect of mucus. No apparent or absolute molecular weight cut-off for macromolecular transfer was exhibited. However, at high molecular weights (greater than 30,000 Daltons) the retardation was greatly enhanced. The results confirm that mucus can be regarded as a gel with finite pores, but that it does not constitute an absolute barrier to even high molecular weight solutes.     

弘扬国学精粹 提高人文素质--高校非中文专业开设"中国古典文学鉴赏"课的必要性与可行性

从高校非中文专业学生知识结构的现状出发，阐述加强人文素质教育的重要性；“中国古典文学鉴赏”课的课程特点及其在人文素质教育中所起的作用决定了在高校非中文专业学生中开设这门课程的必要性和可行性。     

Coalignment of vimentin intermediate filaments with microtubules depends on kinesin.

Intermediate filaments in most types of cultured cells coalign with microtubules. Depolymerization of microtubules results in collapse of vimentin and desmin intermediate filaments to the nucleus where they form a perinuclear cap. Collapse can also be induced by microinjection of antibodies against intermediate filament or microtubule proteins. Thus, two filament systems interact with each other. But the molecules mediating this interaction are unknown. One of the candidates for this role is a microtubule motor kinesin. Recent data showed that kinesin is involved in the plus end-directed movement of the membranous organelles along microtubules such as radial extension of lysosomes in macrophages and centrifugal movement of pigment in melanophores. Here we report that injection of the anti-kinesin antibody into human fibroblasts results in the redistribution of intermediate filaments to a tight perinuclear aggregate but had no effect on the distribution of microtubules. Thus, kinesin is involved not only in organelle movement but also in interaction of the two major cytoskeletal systems, intermediate filaments and microtubules.     

Sound communication inNezara viridula (L.) (Heteroptera: Pentatomidae): Further evidence that signal transmission is substrate-borne

We investigated the sound communication associated with mating inNezara viridula (L.) to clarify conflicting reports on the medium through which acoustic signals are borne. Recordings made from virgin pairs ofN. viridula during precopulatory and compulatory behaviour have revealed that signals transmitted as vibrations through the substrate are a more likely means of communication than signals transmitted by a radiation of sound pressure waves through the air (at least in Australian populations). We present evidence (additional to that already in the literature) that air-borne acoustics are an unlikely mechanism of sexual communication in this species. Specifically, the recorded pulse train patterns showed no consistency or repeatability in relation to different stages of mating behaviour. In contrast, frequency spectrograms of substrate-borne signals reveal repeatable patterns that do correspond with the stage of mating behaviour.